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Jobs

We have two open positions, if you are interested contact us at hiring@sibyllabiotech.it

Computational Biophysicist

Sibylla Biotech is looking for an outstanding and highly-motivated developer in computational biophysics to join its multidisciplinary team. The HQ will be located in Trento until September 2023, and in Milan afterward.

Sibylla is the exclusive licensee of an innovative technology named Pharmacological Protein Inactivation by Folding Intermediate Targeting (PPI-FIT) which enables the identification of small molecules that promote the degradation of a target protein by interfering with its folding pathway. Such a technology paves the way for selectively degrading previously undruggable proteins. The application of our computational platform allows us to characterize previously unexplored protein conformations (folding intermediates) that can be exploited as new drug targets. The computational methods developed by Sibylla Biotech have been used to design new pharmacological strategies for prion diseases [Spagnolli et al. 2021] and for COVID-19 [Massignan et al. 2021].

 

Your Role

You will participate in developing computational methods for the simulations and characterization of protein folding pathways at an atomic level of resolution. You will work closely with the internal software development team to improve Sibylla’s computational platform.

Your tasks will primarily include:

  • Design and programming of enhanced sampling algorithms to study protein folding;
  • Design and programming of clustering schemes;
  • Refinement, improvement, and maintenance of the production pipeline;
  • Participation in scientific meetings for the dedicated tasks.

 

Ideal Candidate

The ideal candidate should hold a Master’s degree in physics, chemistry, engineering, computer science, or computational biology. A Ph.D. in related fields is desirable but not mandatory. The requirements for eligibility are:

  • Deep knowledge of programming. Python is mandatory, experience with C/C++ and web development is welcomed;
  • Deep knowledge of algorithms and data structure;
  • Experience in working with the UNIX environment;
  • Experience with molecular dynamics simulations software (e.g., Gromacs, NAMD, Amber…) ;
  • Basic knowledge in biophysics.

Fluency in English, high predisposition to problem-solving, marked enthusiasm for research, and willingness to work in a team are also mandatory.

 

What we offer

You will be part of a highly cross-disciplinary environment. Scientists in our company come from diversified scientific areas, such as theoretical physics, computer science, medicinal chemistry, and biology. You will have opportunities to break new ground. Our company is fast-growing, which means there will be excellent opportunities for promotions. You will be given responsibilities, and we will fully support your professional growth, always giving extreme importance to your personal needs. Last but not least, we also offer a competitive salary. Sibylla Biotech is an equal opportunity employer; freedom from discrimination is a fundamental human right.

 

How to apply

Interested applicants should submit a cover letter including research accomplishments and interests, CV, and contact information of at least two professional references to hiring@sibyllabiotech.it, specifying ‘Developer in computational biophysics’ in the mail object. Applications not sent via email or lacking documents will NOT be considered. Upon application, you will be sent an email with the instructions to perform a test, which will be the first step of the selection.

Executive Assistant

Sibylla is looking for an Executive Assistant supporting the company executives in the day-by-day activities. The job will start as soon as the selection process will end. The candidate is expected to work in Trento until August 2023. In September 2023 the candidate is expected to move to Milan. Exceptionally, the activity until August 2023 may be performed partially online. Sibylla Biotech is an equal opportunity employer, freedom from discrimination is a fundamental human right.

 

Your tasks

  • Manage scheduling for company executive(s)
  • Coordinate travel arrangements
  • Maintain various records and documents for company executive(s)
  • Organize and prepare for meetings, including gathering documents and attending to logistics of meetings
  • Draft, review and send communications on behalf of company executive(s)
  • Filter job applications
  • Prioritize emails and respond when necessary (in Milan)
  • Answer and respond to phone calls, communicate messages and information to the executive (in Milan)

 

Skills and qualifications

  • Excellent written and verbal communication skills in English language
  • Knowledge of Italian language is a plus, but not compulsory
  • Time-management skills
  • Ability to pay attention to detail
  • Organization skills
  • Ability to multitask
  • Basic understanding of frequently used computer software and programs, such as Microsoft Office
  • Interpersonal skills
  • Previous experience as executive assistant will be taken into consideration

 

What we offer

You will be part of a highly cross-disciplinary environment. Scientists in our company come from diversified scientific areas, such as theoretical physics, computer science, medicinal chemistry, and biology. You will have opportunities to break new ground. Our company is fast-growing, which means there will be excellent opportunities for promotions. You will be given responsibilities, and we will fully support your professional growth, always giving extreme importance to your personal needs. Last but not least, we also offer a competitive salary. Sibylla Biotech is an equal opportunity employer; freedom from discrimination is a fundamental human right.

Interested applicants should send their CVs together with two professional references to hiring@sibyllabiotech.it, specifying “Executive Assistant” in the mail subject. Only applications sent via email will be considered.